A couple days ago, some news finally came out about the connection between Ridley Scott's upcoming "Prometheus" and "Alien." Scott was quoted as saying: "The Prometheus is owned by an entrepreneur called Peter Weyland, and is played by Guy Pearce. That's the connection between the two films, and nothing more. Prometheus is a new film, a new world, and is full of new ideas. And of course new monsters as well." If you are unfamiliar with the "Alien" films, for which "Prometheus" was long thought to be a prequel, Weyland-Yutani is the large corporation that owns the Nostromo and is ever vying to obtain and utilize the dangerous Xenomorph specimens. You can read more about it here, on this awesome Xenopedia site.
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